Nalbufin solution for infection. 10mg/ml amp. 1 ml No. 10

medicament "Nalbufin" is used at the following of indications:

• pain syndrome of strong and average intensity;
• as an additional tool when carrying out anesthesia, for decrease in pain in before - and the postoperative period, anesthesia during childbirth.

Structure

Active ingredient: nalbuphine.

1 ml of solution.

Excipients: sodium citrate, citric acid anhydrous, sodium chloride, water for injections.

Contraindication

Hypersensitivity to a nalbufin to a hydrochloride or to any of medicament ingredients.

Respiratory depression or the significant oppression of central nervous system, the increased intracranial pressure, a head injury, acute alcohol poisoning, alcoholic psychosis, an abnormal liver function and kidneys.

by

for intravenous and intramuscular administration.

Dose needs to be calculated according to intensity of pain, a physical condition of the patient and to consider interaction with other at the same time applied medicines. Usually at a pain syndrome enter intravenously or intramusculary from 0.15 to 0.3 mg/kg of body weight of the patient; the single dose is entered if necessary by each 4-6 hours.

Maximum single dose - 0.3 mg/kg of body weight; the maximum daily dose - 2.4 mg/kg of body weight.

In a myocardial infarction often happen enough 20 mg which enter slowly into a vein, however increase in a dose up to 30 mg can be required. In the absence of accurate positive dynamics of a pain syndrome - 20 mg repeatedly, in 30 min.

as supportive application for anesthesia are necessary for

At use of the medicament "Nalbufin" higher doses, than for anesthesia.

For premedication: 100-200 mkg/kg of body weight. When carrying out an intravenous anesthesia: for introduction to an anesthesia - 0.3-1 mg/kg during 10-15 min., for maintenance of an anesthesia - 250-500 mkg/kg slowly each 30 min.

At anesthesia during childbirth should use medicament in a dose 20 mg intramusculary.

With care appoint medicament sick advanced age, in the general exhaustion, insufficient function of breath. In that case it is necessary to begin use with minimum effective dose in connection with more frequent emergence of side reactions.

Feature of use

Pregnant

due to the lack of researches medicament cannot be used during pregnancy and feeding by a breast.

Children

.

Drivers

during treatment should abstain from control of motor transport or work with other mechanisms.

Overdose

At overdose the respiratory depression, periodic breathing of Cheyna-Stokes arise; drowsiness, a dysphoria, change of consciousness up to a coma; pallor of skin, hypothermia, miosis; lowering of arterial pressure, cardiovascular insufficiency.

Specific antidote is Naloxonum the hydrochloride. In case of intoxication to carry out symptomatic therapy.

At use of medicament the emergence of side reactions is possible

.

from nervous system: dizziness, general weakness, headache, sedation, diplopia, nervousness, depression, excitement, tearfulness, euphoria, hostility, drowsiness, nightmares, hallucinations, sonitus, confusion of consciousness, dysphoria, paresthesias, feeling of unreality, disturbance of the speech, change of mood; spasms, muscle tension, tremor, involuntary muscular contractions.

from a cardiovascular system: increase or lowering of arterial pressure, bradycardia, tachycardia.

from digestive system: dryness in a mouth, gripes, a constipation, dyspepsia, bitter smack, anorexia; symptoms of irritation of digestive tract; a spasm of biliary tract, in inflammatory bowel diseases - paralytic intestinal impassability and toxic megacolon (constipation, a meteorism, nausea, a gastralgia, vomiting).

from a respiratory system: respiratory depression, reduction of minute volume of breath, short wind, asthmatic attacks.

from skin: increased humidity of skin, an itching, urticaria, feeling of heat; ikterichnost of scleras and yellowness of skin; changes in the injection site, including morbidity.

Allergic reactions: shock, a respiratory distress syndrome, a Quincke's edema, a face edema, sneezing, a bronchospasm, a fluid lungs, skin rashes, the increased sweating.

Others: inflows, misting of sight; reduction of a diuresis, frequent desires to urination, a spasm of urinary tract; hepatotoxicity (dark urine, white kcal); medicinal dependence, withdrawal (spastic abdominal pain, nausea, vomiting, rhinorrhea, dacryagogue, weakness, feeling of alarm, fervescence).

Storage conditions

to Store

at a temperature not above 30 °C. To store out of children's reach.

Expiration date - 2 years.