Nalbakson solution for infection. 10mg/ml amp. 1 ml No. 10

Solution for injections Nalbakson indications:

• Pain syndrome of strong and average intensity;
• as an additional tool when carrying out anesthesia
• for decrease in pain in before - and the postoperative period;
• anesthesia during childbirth.

Structure

Active ingredient: nalbuphine.

1 ml of solution for injections the nalbufina of a hydrochloride in terms of 100% contains substance of 10 mg.

Excipients: citric acid, sodium citrate, sodium metabisulphite (E 223), sodium chloride, the hydrochloric acid concentrated, water for injections.

Contraindication

• Hypersensitivity to a nalbufin of a hydrochloride or any of medicament ingredients.
• Respiratory depression or the significant oppression of central nervous system, the increased intracranial pressure, a head injury, acute alcohol poisoning, alcoholic psychosis, an obvious abnormal liver function and kidneys.

Route of administration

Drug is appointed for hypodermic, intravenous and intramuscular administration.

Dosage has to correspond to intensity of pain, a physical condition of the patient and consider interaction with other at the same time applied medicines. Usually at a pain syndrome enter subcutaneously, intravenously or intramusculary from 0.15 to 0.3 mg on 1 kg of body weight of the patient; the single dose is entered if necessary by each 4-6 hours.

Maximum single dose - 0.3 mg/kg of body weight, the maximum daily dose - 2.4 mg/kg of body weight. Use duration - no more than 3 days.

In a myocardial infarction often happens enough 20 mg entered intravenously slowly, but increase in a dose up to 30 mg can be required. In the absence of accurate positive dynamics of a pain syndrome - 20 mg repeatedly in 30 min.

For premedication - 100-200 mkg/kg of body weight. When carrying out an intravenous anesthesia for introduction to an anesthesia - 0.3-1 mg/kg within 10-15 min., for maintenance of an anesthesia - 250-500 mkg/kg each 30 min.

At anesthesia during childbirth should use medicament in a dose 20 mg intramusculary.

With care appoint medicament sick advanced age, in the general exhaustion, insufficient function of breath.

Feature

Pregnant women

use Drug only during childbirth for anesthesia.

Children

.

Drivers

for treatment should refrain from control of motor transport and work with mechanisms.

in case of overdose such symptoms are possible

: respiratory depression, arterial hypotension, a circulatory unefficiency, deepening of a coma, a spasm, a rhabdomyolysis that progresses to a renal failure.

At treatment of overdose is applied:

• at an early stage to patients in consciousness activated carbon inside;
• maintenance therapy (the oxygen, administration of replaceable liquid, means increasing arterial blood pressure)
• administration of Naloxonum (specific antidote).

Side effects

from a cardiovascular system: increase or lowering of arterial pressure, orthostatic hypotension, bradycardia, tachycardia, heartbeat.

from an organ of sight: illegibility or disorder of vision, miosis.

from a digestive tract: a constipation, nausea, vomiting, dryness in a mouth, spasms in a stomach.

General disturbances and reactions in the injection site of drug: the hypothermia can arise local pain, hypostasis, reddening, burning and caumesthesia, inflows, the increased perspiration.

from digestive system: disturbance of functional indicators of a liver, spasm of biliary tract.

from the immune system: anaphylactic reactions.

from nervous system: dizziness, headache, muscular rigidity, increase in intracranial pressure.

Interaction

Under fixed observation and in the reduced doses should use medicament against the background of effect of anesthetics, somnolent drugs, anxiolytics, antidepressants and neuroleptics for prevention of excessive oppression of central nervous system and oppression of activity of a respiratory center. Alcohol also strengthens the oppressing action nalbufiny on central nervous system. Drug should not be used together with other narcotic analgetics because of danger of weakening of analgeziruyushchy action and a possibility of provoking of a withdrawal at patients with dependence to opioids.

to Store

in original packing at a temperature not above 30 °C. To store out of children's reach.

Expiration date: 3 years.