Betalmik cap. eye. 0.5% fl. 10 ml

Betalmik of 0.5% medicine is applied to decrease in intraocular pressure at patients with a chronic open angle glaucoma or eye hypertensia (medicament is used as monotherapy and also in a combination with other medicines).

Structure

1 ml of solution contains (active ingredient) of 5.6 mg of a betaksolol a hydrochloride, is equivalent to a betaksolol of 5 mg (0.5%)).

1 ml of medicine.

Excipients: sodium chloride, dinatrium edetat, a benzalkoniya chloride, sodium hydroxide, water for injections.

Contraindication

• hypersensitivity to active ingredient or other components of medicine;
• dystrophic changes of a cornea;
• reactive respiratory diseases, including heavy bronchial asthma or existence in the anamnesis of heavy bronchial asthma, a serious chronic obstructive illness of lungs;
• sinus bradycardia; syndrome of weakness/dysfunction of sinus node; sinoatrial node dysfunction, sinuatrial blockade; blockade of I and and the III severity without artificial pacemaker;
• cardiogenic shock;
• expressed heart failure.

to Apply

adult. The exact dosage and duration of therapy is always defined by the doctor. The recommended dose makes one drop of the medicine "Betalmik of 0.5%" in a conjunctival sac of the affected eye (eyes) with an interval of 12 hours 2 times a day. If at application in the recommended doses the intraocular pressure of the patient is not controlled properly, it is possible to perform the accompanying therapy by pilocarpine or other miotika and/or adrenaline (epinephrine), and/or karboangidraza inhibitors, or analogs of prostaglandins.

If more than one ophthalmologic means is applied by

outwardly, the interval between use of various medicines has to be not less than 5 minutes.

After instillation is recommended to be pressed easily the site of a dacryocyst in an internal corner of an eye and to release in 2-3 minutes after burying for decrease in system absorption.

Feature of application

Pregnant

Betaksolol should not be applied during pregnancy, except cases of emergency and only if the potential advantage for mother exceeds potential risk for a fruit. However, if betaksolol applied before childbirth, in the first days after the birth it is necessary to carry out careful observation of the newborn.

Beta-blockers get into breast milk. However at application of therapeutic doses of a betaksolol in the form of eye drops hardly the amount of medicine which can cause clinical symptoms of blockade of beta receptors of the newborn will get to breast milk.

Efficiency and safety of application of means is not established to children by

.

Drivers

At use of medicine the sight can grow dim with

for a while that can negatively affect ability to steer vehicles or to work with other mechanisms. It is possible to start such activity not earlier than in 15 minutes after application of drops, the sight does not clear up yet.

to

Overdose

About overdose of a betaksolol after ophthalmologic application it was not reported. Symptoms which can be expected at overdose by system beta blockers include: arterial hypotension, bradycardia and an acute heart failure, the complicated breath, a bronchospasm, a syncope, generalized spasms.

child, it is recommended to address the pediatrician.

At overdose the medicine "Betalmik of 0.5%" at topical administration is recommended to wash an eye with warm flowing water well.

When using all contents of 5 ml / 10 bottle ml the general dose of a betaksolol makes 25 mg / 50 mg. The recommended daily oral dose makes from 10 to 20 mg of a betaksolol at intake for treatment of arterial hypertension.

Therapy of intoxication

needs to control the main vital functions regularly.

is Applied intravenously:

• Atropini sulfas in a dose of 0.5˗2 mg for blockade of vagus nerve;
• a glucagon in an initial dose of 1˗10 mg, then 2˗2,5 mg/hour for long injection;
• ß sympathomimetics (for example Dobutaminum, izoprenalin, ortsiprenalin) or even adrenaline depending on degree of intoxication and body weight;
• ß2 simpatomimetiki in the form of aerosol or intravenously at a bronchospasm;
• Aminophyllinum in case of a bronchospasm.

In spasms recommends slow introduction of diazepam.

Side effects

As well as other eye medicaments used locally betaksolol it is soaked up in a system blood-groove. Thus, side effects, similar to those which arise at system application of beta-blockers can develop. The list of side reactions includes reactions most of which often met at application of beta-blockers at topical administration in eyes.

from the immune system: reactions of hypersensitivity, including a Quincke's edema, the localized and general rash, anaphylactic reactions.

Disturbance of metabolism and food frustration: hypoglycemia.

Mental disorders: depression, insomnia, nightmares, loss of memory, hallucination, psychosis, confusion of consciousness.

from nervous system: headache, dizziness, syncope/syncope, violations of cerebral circulation, brain ischemia, strengthening of symptomatology of a myasthenia, paresthesia, concern.

from organs of sight: symptoms of irritation of eyes, conjunctival violations, conjunctival hypostasis, conjunctivitis, burning, pricking, an itch, the strengthened dacryagogue, reddening, inflammation of eyes, blepharitis, dot keratitis, keratitis, decrease in sensitivity of a cornea, eye pain, xerophthalmus, misting of sight, disorder of vision, decrease in visual acuity, photophobia, asthenopia, nictitating spasm, ptosis, diplopia, choroidal amotio after the procedures of filtration, a cornea erosion, sensation of discomfort in an eye, feeling of a foreign body in eyes, unusual feeling in an eye, discharges from eyes, formation of scales at the edges a century, a cataract.

Warm frustration: arrhythmia, bradycardia, tachycardia, stethalgia, cardiopalmus, hypostases, blockade, cardiac arrest, stagnant heart failure.

Vascular frustration: arterial hypotension, Reynaud's phenomenon, a cold snap of extremities, strengthening of the alternating lameness.

from respiratory organs, a chest cavity, mediastinum: asthma, short wind, a bronchospasm (mainly at patients with already available bronkhospastichesky disease), cough, rhinitis, a rhinorrhea.

from digestive tract: a dysgeusia, nausea, dyspepsia, diarrhea, dryness in a mouth, an abdominal pain, vomiting, a glossitis.

from skin and hypodermic cellulose: alopecia, psoriazopodobny rashes or exacerbation of psoriasis, skin rash, itch, small tortoiseshell, toxic epidermal necrolysis, dermatitis.

from a musculoskeletal system and connective tissue: myalgia.

from a reproductive system and mammary glands: sexual dysfunction / impotence, decrease in a libido.

Disturbance of the general character and a state, connected with the place of application: adynamy/fatigue, increase in level of antinuclear antibodies.

to Store

at a temperature not above 25 °C, in the inaccessible for children and protected from light place. Not to freeze.

Expiration date - 2 years.

to store

After opening no more than 28 days.