Alligat of the capsule vitamin complex packing of 30 pieces

Vitamin E participates in biosynthesis a subject and proteins, proliferation of cages, fabric breath, other major processes of fabric metabolism, prevents hemolysis of erythrocytes, reduces hyperpermeability and fragility of capillaries. It is necessary for development and functioning of connective tissue, unstriated and skeletal muscles and also for strengthening of walls of blood vessels. Takes part in metabolism of nucleic acids and prostaglandins, a cellular respiratory cycle, in synthesis of arachidonic acid. Is natural antioxidant, slows down peroxide oxidation of lipids by free radicals. Activates phagocytosis and it is used for maintenance of normal resistance of erythrocytes. In high doses prevents aggregation of platelets. Alpha tocopherol also stimulates immunity as the general, and humoral, and cellular. Thanks to it the activity of T lymphocytes increases. Besides, in total with vitamin A the normal formation of a reproductive system and embryonic development is provided. Vitamin E is applied at hypovitaminosis, a convalescence after the diseases proceeding with a feverish syndrome, an asthenic and neurotic syndrome, degenerative and proliferative changes of joints, diseases of the copular device and muscles; dysfunction of gonads at men; at women - at various violations of a menstrual cycle, at deterioration in conditions of pre-natal fetation.

Appoint vitamin E and at seborrhea, atrophic changes of skin (a scleroderma, etc.), trophic ulcers of a shin, photodermatoses, psoriasis, a dermatomyositis, etc. collagenoses.

From a GIT slowly soak up about 50%, the maximum level in blood is created in 4 h. It is necessary to have bile acids for absorption. In the course of absorption forms a complex with lipoproteids, being intracellular carriers of vitamin E. Comes, mainly, to a lymph. It is deposited in adrenal glands, a hypophysis, seed plants, fatty and muscle tissue, erythrocytes, a liver. Is exposed to metabolism and it is allocated from an organism and bile (over 90%) and urine (about 6%). Vitamin A is responsible for fabric exchange, is capable to increase cell-mediated and antibody-mediated immunity, strengthens a myelopoiesis, improves function of macrophages. By means of intake of vitamin A it is possible to reduce risk of a disease of mucous airways and a digestive tract. At its application the keratinization slows down, cells rejuvenate. The beneficial influence of the medicine Alligat on reproductive function is also caused by participation of vitamin A in this complex. Besides, Retinolum palmitate participates in forming of a visual signal, a bone tissue, promotes growth of bones, positively influences work of sweat, sebaceous, lacrimal glands. Also, vitamin A, thanks to nonsaturated bonds of a molecule of Retinolum, interacts with different types of radicals, and stimulates antioxidant function of vitamin E which, in turn, being the second important component of Alligat, interferes with Retinolum oxidation, thereby preventing formation of toxic products.

Indications

• vitamin E Hypovitaminosis.
• High physical activity.
• Disturbance of a menstrual cycle.
• Threat of termination of pregnancy.
• Climacteric vegetative violations.
• Dysfunction of gonads at men.
• Neurasthenia at overfatigue, an asthenic syndrome.
• Amyotrophic side syndrome, primary muscular dystrophy.
• Posttraumatic secondary myopathy.
• Disease of the copular device and muscles.
• Degenerative and proliferative changes of joints and copular device of a backbone and large joints, spasm of peripheral vessels.
• Dermatomyositis, some dermatosis, psoriasis.
• During the period at the diseases proceeding with fever.
• In gerontology (advanced age).
• In epilepsy (for increase in efficiency of anticonvulsants).
• In complex treatment at many diseases (as antioxidant).
• Atrophy of an optic nerve, "night blindness" (hemeralopia), keratomalacia, xerophthalmia, retinitis pigmental.

Structure

• Vitamin E - 100 mg (natural D - alpha tocopherol - 150 ME).
• Vitamin A - 300 mkg (Retinolum palmitate - 1000 ME).

• At violation of a spermatogenesis by

  on 1-2 tablet (100 - 300 ME) a day (in combination with hormonal therapy) within a month;

• At deterioration in conditions of pre-natal fetation on 1-2 tablet (100 - 200 ME) within the first 2-3 months of pregnancy daily or every other day.
• In muscular dystrophies, an amyotrophic side sclerosis, a dermatomyositis, etc. collagenoses vitamin E is applied on 100 mg (100 ME) a day within 1-2 months; repeated courses are appointed in 2 - 3 months; In diseases of peripheral vessels on 1-2 tablet (100 ME) a day (in combination with vitamin A) within 20 - 40 days, in 3-6 months the course of treatment can be repeated.
by
• In diseases of skin appoint medicine on 1 tablet (100 ME) a day within 20-40 days. Duration of treatment of hypovitaminosis E is individual and depends on weight of a state. If necessary it is possible to increase a dose to 1 g (1000 ME) in day.

for a long time together with other polyvitaminic medicines since approach of overdose of oil-soluble vitamin E is possible.

Contraindication

Acute myocardial infarction; children's age; hypersensitivity to medicine components. With care apply at patients with the heavy cardiosclerosis postponed a myocardial infarction at the increased risk of developing a thrombembolia; the prothrombinopenia caused by insufficiency of vitamin K can worsen at use of vitamin E in a dose more than 400 ME.

Side effect

Allergic reactions. At reception of high doses - diarrhea, pains in epigastriums, a creatinuria. At emergence of side effects a dose of medicine it is necessary to reduce or cancel medicine.

Interaction with other medicines

increases efficiency of anticonvulsants at patients with epilepsy. Enhances effect steroid and non-steroidal anti-inflammatory drugs, antioxidants. Increases efficiency and reduces toxicity of cardiac glycosides and also vitamins A and D. Prescribing of vitamin E in high doses can cause vitamin A deficiency in an organism.

Simultaneous use of vitamin E in a dose more than 400 ME/days with anticoagulants (derivatives of coumarin and an indandion) increases risk of developing a prothrombinopenia and bleedings.

Overdose

Symptoms:

• At reception during the long period in doses of 400 - 800 ME/days - illegibility of visual perception, dizziness, a headache, nausea, extraordinary fatigue, diarrhea, a gastroliya, an adynamy;
• At reception more than 800 ME/days during the long period - increase in risk of developing bleedings at patients with hypovitaminosis To, violation of metabolism of tiroidny hormones, disorders of sexual function, thrombophlebitis, a thrombembolia, necrotic colitis, sepsis, a hepatomegalia, a hyperbilirubinemia, a renal failure, hemorrhages in a mesh cover of an eye, a hemorrhagic stroke, ascites, hemolysis.

Treatment: medicament withdrawal; appoint the glucocorticoids accelerating metabolism of vitamin E in a liver; appoint Vikasolum for reduction of danger of hemorrhages.

Use of medicine at pregnancy and feeding by a breast

during pregnancy and breastfeeding administration of medicament only according to the recommendation of the doctor.

release Form

Alligat No. 30. On 15 capsules in the blister, on 2 blisters together with the instruction for use in a pack from cardboard.

Storage conditions

B the dry place protected from light at a temperature from 15 to 25 °C. To store in the places inaccessible for children.

Expiration date is specified by

on packing. Not to use after expiry date.